Role of Transcription Factors in Gastrointestinal Malignancies 1st ed. 2017 Edition

  • NH_06838
34 $

by Ganji Purnachandra Nagaraju (Editor), Pallaval Veera Bramhachari (Editor)

 

Role of Transcription Factors in Gastrointestinal Malignancies 1st ed. 2017 Edition

by Ganji Purnachandra Nagaraju (Editor), Pallaval Veera Bramhachari (Editor)

This book illustrates the importance of transcription factors in gastrointestinal cancer progression and metastasis with regard to understanding the mechanism and target definition in drug discovery. Further, it describes the complex issues associated with cancer cell growth and metastasis. The respective chapters provide detailed information on the various types of transcription factors (NF-kB, HIF-1, STAT-3, E2F1, and Sp1) and gastric-associated cancers (esophagus, stomach, colorectal, liver and pancreatic cancers) in connection with specific functional studies like cell cycle, angiogenesis, migration, invasion and apoptosis. These transcription factors control the expression of several signaling pathways involved in tumor growth, making them ideal targets for gastrointestinal cancer therapy. In closing, the book provides comprehensive descriptions of the major challenges associated with gastrointestinal cancer therapy.

Product details

  • Hardcover: 517 pages
  • Publisher: Springer; 1st ed. 2017 edition (March 28, 2018)
  • Language: English